Case Study

Laser Enhanced PRP for Congenital Adrenal Hypoplasia

In this case study, we aimed to evaluate the effectiveness of laser-enhanced platelet-rich plasma (PRP) therapy; our proprietary NeuroRestoration procedures, on a 14-year-old male patient diagnosed with congenital adrenal hypoplasia.

Use of Laser enhanced PRP for symptoms related to congenital adrenal hypoplasia

In this case study, we aimed to evaluate the effectiveness of laser-enhanced platelet-rich plasma (PRP) therapy; our proprietary NeuroRestoration procedures, on a 14-year-old male patient diagnosed with congenital adrenal hypoplasia. The patient presented with complaints of low energy, fatigue, lethargy, low motivation, depression, and anxiety, which prompted us to explore innovative treatment options. The laser PRP procedure was conducted on May 12, 2023, and to assess its impact on brain function, we performed pre and post quantitative electroencephalogram (QEEG) studies. Notably, our observations revealed remarkable positive changes in the patient's brain activity, suggesting promising outcomes associated with laser-enhanced PRP therapy in addressing the presenting symptoms of this individual.

Platelet-rich plasma (PRP) is a regenerative therapy that has gained popularity in recent years for its potential benefits in promoting tissue healing and regeneration. PRP is derived from a patient's own blood and contains a concentrated amount of platelets, which are rich in growth factors and cytokines. Platelets play a crucial role in the body's natural healing process, and when injected into injured or damaged tissues, PRP can stimulate collagen production, enhance cell proliferation, and promote tissue regeneration. In addition to platelets, PRP also contains other cell types such as white blood cells and mesenchymal stem cells, which further contribute to the therapeutic effects of PRP.

We use a specific laser that was designed for this procedure to irradiate the person’s own platelet-rich plasma (PRP), the cells within this solution are then enhanced and activated in a process known as laser activation of PRP (L-PRP). The laser light penetrates the PRP, stimulating the cells within the PRP to release growth factors, cytokines, and other bioactive molecules at an increased rate. This laser-induced activation of PRP enhances the biological properties and therapeutic potential of the solution. The activated PRP can then be effectively utilized in various medical and aesthetic treatments, such as wound healing, tissue regeneration, and skin rejuvenation. The laser activation process optimizes the healing properties of PRP, providing a targeted and efficient approach to harness its regenerative capabilities.

The initial QEEG study was conducted on February 15, 2023, to evaluate the neurophysiological status of the patient. The findings revealed several abnormal patterns in brain activity, specifically in the default mode network, dorsal attention networks, and left visual cortex. The default mode network (DMN) refers to a set of interconnected brain regions that are active when an individual is at rest and not engaged in any specific cognitive task. It is associated with processes such as self-reflection, mind-wandering, and introspection. Reduced activity in the DMN, as observed in this case, may indicate disruptions in self-referential thinking and introspection.

On the other hand, the dorsal attention networks are responsible for directing attention, focus, and cognitive control. Abnormal brainwave activity in these networks suggests difficulties in sustaining attention, task switching, and cognitive flexibility.

Furthermore, the left visual cortex is a region of the brain involved in processing and interpreting visual information received from the left visual field. Abnormal activity in this area may indicate altered visual perception or processing.

These findings from the initial QEEG study provide valuable insights into the specific areas of brain dysfunction in the patient's case of congenital adrenal hypoplasia.

Following the laser-enhanced PRP therapy, a post QEEG analysis was conducted on March 29, 2023, to assess changes in the patient's brainwave activity. The analysis revealed notable positive findings, indicating significant improvements in various brain regions.

Firstly, the default mode network (DMN), which previously showed reduced activity in the initial QEEG, demonstrated normalization in brainwave activity. This suggests that the laser-enhanced PRP therapy may have helped restore proper functioning of the DMN, consequently improving self-reflection, mind-wandering, and introspection.

Moreover, the dorsal attention network, which exhibited abnormal brainwave activity in the initial QEEG, showed remarkable changes and normalization in brainwave patterns. This indicates that the laser-enhanced PRP therapy may have effectively enhanced attention, cognitive control, and task switching abilities in the patient.

Furthermore, the post QEEG analysis revealed complete normalization of brainwave activity in the visual cortex, the region responsible for processing and interpreting visual information. This signifies that the laser-enhanced PRP therapy may have successfully restored normal visual perception and processing in the patient.

Overall, these encouraging post QEEG findings indicate the positive impact of laser-enhanced PRP therapy on the patient's neurophysiological functioning, supporting the efficacy of this novel treatment approach in addressing the symptoms associated with congenital adrenal hypoplasia.

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Case Study Details

NeuroSolution Center of Austin, Research Division
August 1, 2023
Dr. Brandon Crawford working with a pediatric patient at NeuroSolsution Center of Austin, Texas.
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